ρ-Da1a – AdTx1
Selective antagonist of the alpha(1A)-adrenoceptor
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產品名稱: ρ-Da1a – AdTx1
Selective antagonist of the alpha(1A)-adrenoceptor
產品型號: ADT001-00010
產品展商: 其他品牌
產品文檔: 無相關文檔
簡單介紹
ρ-Da1a – AdTx1
Selective antagonist of the alpha(1A)-adrenoceptor
AdTx1 (rho-Da1a – ρ-Da1a) is a 65 amino-acid peptide originally isolated from the venom of the green mamba, an African snake (Dendroaspis angusticep). AdTx1 is stabilized by four disulfide bridges and belongs to the family of the three-finger-fold peptide. AdTx1 has subnanomolar affinity (K(i)= 0.35 nM) and high specificity for the
ρ-Da1a – AdTx1
Selective antagonist of the alpha(1A)-adrenoceptor
的詳細介紹
ρ-Da1a – AdTx1
Selective antagonist of the alpha(1A)-adrenoceptor
AdTx1 (rho-Da1a – ρ-Da1a) is a 65 amino-acid peptide originally isolated from the venom of the green mamba, an African snake (Dendroaspis angusticep). AdTx1 is stabilized by four disulfide bridges and belongs to the family of the three-finger-fold peptide. AdTx1 has subnanomolar affinity (K(i)= 0.35 nM) and high specificity for the human alpha(1A)-adrenoceptor subtype and is 1000 times more potent on this subtype than on other adrenoceptor subtypes. AdTx1 is a potent relaxant of smooth muscles.
