α-conotoxin-IMI
α7 nAChR selective blocker
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產品名稱: α-conotoxin-IMI
α7 nAChR selective blocker
產品型號: 08CON011-00500
產品展商: 其他品牌
產品文檔: 無相關文檔
簡單介紹
α-conotoxin-IMI
α7 nAChR selective blocker
α-conotoxin IMI (alpha-conotoxin IMI) is a conopeptide that has been isolated from the venom of the cone snail Conus imperialis. α-conotoxin IMI acts on postsynaptic membranes, and binds onto and inhibits nicotinic acetylcholine receptors (nAChR). α-conotoxin IMI is a selective blocker of α7 homomeric nicotinic acetylcholine receptors (IC50 ~ 200 nM). It
α-conotoxin-IMI
α7 nAChR selective blocker
的詳細介紹
α-conotoxin-IMI
α7 nAChR selective blocker
α-conotoxin IMI (alpha-conotoxin IMI) is a conopeptide that has been isolated from the venom of the cone snail Conus imperialis. α-conotoxin IMI acts on postsynaptic membranes, and binds onto and inhibits nicotinic acetylcholine receptors (nAChR). α-conotoxin IMI is a selective blocker of α7 homomeric nicotinic acetylcholine receptors (IC50 ~ 200 nM). It has no effect on nAChRs composed of α2/?2, α3/?2, α4/?2, α2/?4, α3/?4, or α4/?4 subunits. α-conotoxins IMI acts independently of voltage value. This toxin is highly active against the neuromuscular receptor in frog.
