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Biotin azide

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產品名稱: Biotin azide
產品型號: C3730 D3730 E3730 F3730
產品展商: lumiprobe
產品文檔: 無相關文檔

簡單介紹

Biotin azide C3730 D3730 E3730 F3730


Biotin azide  的詳細介紹

Biotin azide

Azides
Cat. # Quantity Price Lead time
C3730 10 mg  40.00$ in stock
 
D3730 25 mg  100.00$ in stock
 
E3730 50 mg  140.00$ in stock
 
F3730 100 mg  180.00$ in stock
 
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Biotin azide is a derivative of biotin (vitamin H) covalently bound with azide group. This reagent allows labeling of various alkynylated molecules (such as DNA, oligonucleotides, and proteins) with biotin. Biotin binding to avidin or streptavidin can be used in downstream affinity applications for the isolation of biotinylated molecules or their binding with streptavidin conjugates.

This structure of biotin azide features long hydrophilic linker which separates biotin residue from the target molecule for efficient binding with streptavidin. Its linker (PEG) also enhances aquous solubility to facilitate conjugation.

The azide can be conjugated with various molecules using our recommended protocol.

Biotin azide structure
Download in 
ChemDraw format

Recommended protocol

Click-Chemistry Labeling of Oligonucleotides and DNA

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General properties

Appearance: colorless solid
Molecular weight: 400.50
Molecular formula: C16H28N6O4S
Solubility: soluble in DMF, DMSO, moderately soluble in water
Quality control: NMR 1H (95%) and 13C, TLC, functional testing
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks.
MSDS: Download

Product citations

  1. Wang, E.; Hunter, C.P. SID-1 Functions in Multiple Roles To Support Parental RNAi in Caenorhabditis elegans. Genetics, 2017, 207(2), 547–557. doi: 10.1534/genetics.117.300067
  2. Bruckman, M.A.; Czapar, A.E.; VanMeter, A.; Randolph, L.N.; Steinmetz, N.F. Tobacco mosaic virus-based protein nanoparticles and nanorods for chemotherapy delivery targeting breast cancer. Journal of Controlled Release, 2016, 231, 103–113. doi:10.1016/j.jconrel.2016.02.045
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