Recombinant Human Interleukin-21 protein(IL21) (Active)
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產品名稱: Recombinant Human Interleukin-21 protein(IL21) (Active)
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簡單介紹
Recombinant Human Interleukin-21 protein(IL21) (Active)
Recombinant Human Interleukin-21 protein(IL21) (Active)
的詳細介紹
產品類型:Interleukin
產品名稱:Recombinant Human Interleukin-21 protein(IL21) (Active)
uniprot號:
規格:
￥620
圖像:
基因名稱:
IL21
別名:
IL-21
種屬:
Homo sapiens (Human)
蛋白描述:
Full Length of Mature Protein
PubMed ID:
11081504; 17673207; 15815621; 15489334; 15178704; 15147560; 17565991; 22235133; 24746753
分子量:
15.4 kDa
標簽信息:
Tag-Free
來源:
E.Coli
純度:
>97% as determined by SDS-PAGE and HPLC.
緩沖液:
0.2 μm filtered PBS, pH 7.4 ,lyophilized
內毒素:
Less than 1.0 EU/μg as determined by LAL method.
生物活性:
Fully
biologically active when compared to standard. The ED50 as determined by by a cell proliferation assay using human N1186 T cells is less than 20 ng/ml, corresponding to a specific activity of >5.0x10
4 IU/mg.
IL21_HUMAN
參考文獻:
Cytokine with immunoregulatory activity. May promote the transition between innate and adaptive immunity. Induces the production of IgG(1) and IgG(3) in B-cells (By similarity). May play a role in proliferation and maturation of natural killer (NK) cells in synergy with IL15. May regulate proliferation of mature B- and T-cells in response to activating stimuli. In synergy with IL15 and IL18 stimulates interferon gamma production in T-cells and NK cells. During T-cell mediated immune response may inhibit dendritic cells (DC) activation and maturation. {ECO:0000250, ECO:0000269|PubMed:11081504, ECO:0000269|PubMed:15178704}.
氨基酸序列:
QGQDRHMIRM RQLIDIVDQL KNYVNDLVPE FLPAPEDVET NCEWSAFSCF QKAQLKSANT GNNERIINVS IKKLKRKPPS TNAGRRQKHR LTCPSCDSYE KKPPKEFLER FKSLLQKMIH QHLSSRTHGS EDS
表達區域:
23-155aa
研究領域:
Immunology
