Recombinant Human C-C motif chemokine 14 protein(CCL14) (Active)
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產品名稱: Recombinant Human C-C motif chemokine 14 protein(CCL14) (Active)
產品型號:
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簡單介紹
Recombinant Human C-C motif chemokine 14 protein(CCL14) (Active)
Recombinant Human C-C motif chemokine 14 protein(CCL14) (Active)
的詳細介紹
產品類型:Chemokine
產品名稱:Recombinant Human C-C motif chemokine 14 protein(CCL14) (Active)
uniprot號:
規格:
￥620
圖像:
基因名稱:
CCL14
別名:
Chemokine CC-1/CC-3, HCC-11-74 NCC-2, Small-inducible cytokine A14
種屬:
Homo sapiens (Human)
蛋白描述:
Partial
PubMed ID:
8551235; 9600961; 10213461; 15489334; 10978165; 11085751; 17691823
分子量:
7.8 kDa
標簽信息:
Tag-Free
來源:
E.Coli
純度:
>95% as determined by SDS-PAGE and HPLC.
緩沖液:
0.2 μm filtered PBS, pH 7.4 ,lyophilized
內毒素:
Less than 1.0 EU/μg as determined by LAL method.
生物活性:
Fully
biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human monocytes is in a concentration range of 5.0-20 ng/ml.
CCL14_HUMAN
參考文獻:
Has weak activities on human monocytes and acts via receptors that also recognize MIP-1 alpha. It induced intracellular Ca(2+) changes and enzyme release, but no chemotaxis, at concentrations of 100-1,000 nM, and was inactive on T-lymphocytes, neutrophils, and eosinophil leukocytes. Enhances the proliferation of CD34 myeloid progenitor cells. The processed form HCC-1(9-74) is a chemotactic factor that attracts monocytes eosinophils, and T-cells and is a ligand for CCR1, CCR3 and CCR5. {ECO:0000269|PubMed:11085751}.
氨基酸序列:
GPYHPSECCF TYTTYKIPRQ RIMDYYETNS QCSKPGIVFI TKRGHSVCTN PSDKWVQDYI KDMKEN
表達區域:
28-93aa
研究領域:
Immunology
