yc-1 hif-1 inhibitor , reduced whole kidney glomerular hypertrophy
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產品名稱: yc-1 hif-1 inhibitor , reduced whole kidney glomerular hypertrophy
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簡單介紹
CAS:170632-47-0Formula:C19H16N2O2MW:304.4Appearance:Off-WhitetoYellowSolidPurity:98%
yc-1 hif-1 inhibitor , reduced whole kidney glomerular hypertrophy
的詳細介紹
A direct activator of soluble Guanylyl Cyclase (sGC), independent of Nitric Oxide.Involvement of P2X7 Receptors A novel mode of action of YC-1 in HIF inhibition: stimulation of FIH-dependent p300 dissociation from HIF-1,Additional Information
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Synonyms | 3-(5'-hydroxymethyl-2'furyl)-1-benzyl indazole |
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Product # | Y-1000 |
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CAS # | 170632-47-0 |
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Chemical Name | 3-(5'-hydroxymethyl-2'furyl)-1-benzyl indazole |
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Formula | C19H16N2O2 |
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MW | 304.4 |
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Appearance | Off-White to Yellow Solid |
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Purity | 98% |
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Solubility | DMSO |
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Melting Point | 110-113 °C |
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Storage Temp | +4°C |
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Therapeutic Area | Oncological Disorders |
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Use | YC-1 is a potential anticancer drug targeting hypoxia-inducible factor 1 |
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Additional Information
| MDL Number | MFCD06407798 |
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| ChemACX | X1206446-5 |
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| InChI | InChI=1S/C19H16N2O2/c22-13-15-10-11-18(23-15)19-16-8-4-5-9-17(16)21(20-19)12-14-6-2-1-3-7-14/h1-11,22H,12-13H2 |
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| SMILES | c1ccc(cc1)Cn2c3ccccc3c(n2)c4ccc(o4)CO |
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