Anti-FAM120A Antibody
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產品名稱: Anti-FAM120A Antibody
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簡單介紹
Anti-FAM120A Antibody
的詳細介紹
Overview
| Name: |
Anti-FAM120A Antibody See all FAM120A primary antibodies
|
| Description: |
Rabbit polyclonal antibody to FAM120A |
| Specificity: |
This antibody will not cross-reacti with FAM120B / PGCC1. |
| Applications: |
E, WB, IHC |
| Reactivity: |
Human, Mouse, Rat |
| Immunogen: |
Raised against an 18 amino acid peptide from near the center of human FAM120A. |
| Host: |
Rabbit |
| Clonality: |
Polyclonal |
| Conjugate: |
Unconjugated |
| Purification: |
Affinity chromatography purified via peptide column |
| Formulation: |
Supplied in PBS containing 0.02% sodium azide. |
| Storage: |
Can be stored at -20?C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
Target
| Function: |
Critical component of the oxidative stress-induced survival signaling. Activates src family kinases and acts as a scaffolding protein enabling src family kinases to phosphorylate and activate PI3-kinase. Binds RNA and promotes the secretion of IGF-II (By similarity). May participate in mRNA transport in the cytoplasm. |
| Tissue Specificity: |
Present in Purkinje cells in the cerebellum, and in cortical neurons (at protein level). |
| Sequence Similarities: |
Belongs to the constitutive coactivator of PPAR-gamma family. |
| Post-Translational Modification: |
Arg-980 is dimethylated, probably to asymmetric dimethylarginine. |
| Cellular Location: |
Cytoplasm. Cell membrane.
Translocates to plasma membrane upon ultraviolet exposure. |
| Database Links: |
Entrez Gene: 23196?HumanEntrez Gene: 218236?MouseEntrez Gene: 291019?RatGenBank: NP_055427.2?HumanOmim: 612265?HumanSwissProt: Q9NZB2?HumanSwissProt: Q6A0A9?MouseUnigene: 372003?HumanUnigene: 707324?HumanUnigene: 426571?Mouse |
| Synonyms: |
C9orf10 AntibodyChromosome 9 open reading frame 10 AntibodyConstitutive coactivator of PPAR gamma like protein 1 AntibodyConstitutive coactivator of PPAR-gamma-like protein 1 AntibodyDNA polymerase transactivated protein 1 AntibodyDNA polymerase transactivated protein 5 AntibodyDNAPTP1 AntibodyDNAPTP5 AntibodyF120A_HUMAN AntibodyFAM120A AntibodyFamily with sequence similarity 120A AntibodyHypothetical protein LOC23196 AntibodyKIAA0183 AntibodyLOC23196 AntibodyMGC111527 AntibodyMGC133257 AntibodyOSSA AntibodyOxidative stress-associated Src activator AntibodyProtein FAM120A Antibody |
| Information: |
Target information shown above is from the UniProt Consortium. |
