Anti-FABP6 Antibody
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產品名稱: Anti-FABP6 Antibody
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簡單介紹
Anti-FABP6 Antibody
的詳細介紹
Overview
| Name: |
Anti-FABP6 Antibody See all FABP6 primary antibodies
|
| Description: |
Rabbit polyclonal antibody to FABP6 |
| Specificity: |
The antibody detects endogenous levels of total FABP6 protein. |
| Applications: |
WB, IHC |
| Reactivity: |
Human, Mouse |
| Immunogen: |
Full length fusion protein |
| Host: |
Rabbit |
| Clonality: |
Polyclonal |
| Conjugate: |
Unconjugated |
| Purification: |
Antigen affinity purification. |
| Concentration: |
1.1mg / ml |
| Formulation: |
Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol. |
| Storage: |
Store at -20?C |
Target
| Function: |
Binds to bile acids and is involved in enterohepatic bile acid metabolism. Required for efficient apical to basolateral transport of conjugated bile acids in ileal enterocytes (By similarity). In vitro binds to bile acids in the order: deoxycholic acid > cholic acid > chenodeoxycholic acid and respective BA conjugation modifies affinities in the order taurine-conjugated > glycine-conjugated > unconjugated bile acids. Stimulates gastric acid and pepsinogen secretion (By similarity). |
| Tissue Specificity: |
Isoform 1 is expressed in the jejunum, ileum, cecum and ascending colon intestine. Isoform 2 is xpressed in the gallbladder, duodenum, jejunum, ileum, cecum, ascending, transverse and descending colon, sigmoid colon and rectum. Isoform 2 is expressed in colorectal adenocarcinomas and their adjacent normal mucosa (at protein level). |
| Sequence Similarities: |
Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. |
| Cellular Location: |
Cytoplasm. Membrane. |
| Database Links: |
Entrez Gene: 2172?HumanEntrez Gene: 16204?MouseOmim: 600422?HumanSwissProt: P51161?HumanSwissProt: P51162?MouseUnigene: 519719?HumanUnigene: 142716?Mouse |
| Synonyms: |
FABP6 AntibodyFABP6_HUMAN AntibodyFatty acid binding protein 6, ileal (gastrotropin) AntibodyFatty acid-binding protein 6 AntibodyGastrotropin AntibodyGT AntibodyI 15P AntibodyI BABP AntibodyI BALB AntibodyI BAP AntibodyI-15P AntibodyI-BABP AntibodyI15P AntibodyIBABP AntibodyIBALB AntibodyIBAP AntibodyILBP AntibodyILBP3 AntibodyIleal lipid binding protein AntibodyIleal lipid-binding protein AntibodyILLBP AntibodyIntestinal 15 kDa protein AntibodyIntestinal bile acid binding protein AntibodyIntestinal bile acid-binding protein Antibody |
| Information: |
Target information shown above is from the UniProt Consortium. |
