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Anti-ETV4 Antibody

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產品名稱: Anti-ETV4 Antibody
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簡單介紹

Anti-ETV4 Antibody


Anti-ETV4 Antibody  的詳細介紹
Name: Anti-ETV4 Antibody
See all ETV4 primary antibodies
Description: Rabbit polyclonal antibody to ETV4
Specificity: The antibody detects endogenous level of total ETV4 protein.
Applications: WB, IHC, IF
Reactivity: Human, Mouse, Rat
Immunogen: Recombinant protein of human ETV4.
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Purification: Antibodies were purified by affinity purification using immunogen.
Concentration: 1.0mg / ml
Formulation: Supplied at 1.0mg / mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage: Store at -20?C
Function: Transcriptional activator that binds to the enhancer of the adenovirus E1A gene; the core-binding sequence is 5'[AC]GGA[AT]GT-3'.
Sequence Similarities: Belongs to the ETS family.
Post-Translational Modification: Sumoylated; enhanced upon ERK/MAP kinase pathway activation, it positively regulates the transcriptional activator capacity. Sumoylation at Lys-96 probably requires phosphorylation at Ser-101. Transiently polysumoylated and desumoylated by SENP1. Sumoylation is a prerequisite to polyubiquitination which in turn increases proteasomal-mediated degradation. Probably polyubiquitinated by RNF4 and deubiquitinated by USP2.
Cellular Location: Nucleus.
Database Links:
  • Entrez Gene: 2118?Human
  • Entrez Gene: 18612?Mouse
  • Entrez Gene: 360635?Rat
  • Omim: 600711?Human
  • SwissProt: P43268?Human
  • SwissProt: P28322?Mouse
  • Unigene: 434059?Human
  • Unigene: 5025?Mouse
  • Unigene: 195602?Rat
    		•
    Synonyms:
  • Adenovirus E1A enhancer binding protein Antibody
  • Adenovirus E1A enhancer-binding protein Antibody
  • E1A F Antibody
  • E1A-F Antibody
  • ETS translocation variant 4 Antibody
  • ets variant gene 4 (E1A enhancer binding protein E1AF) Antibody
  • ETV4 Antibody
  • ETV4_HUMAN Antibody
  • Pea3 Antibody
  • PEA3 protein Antibody
  • PEAS3 Antibody
  • Polyomavirus enhancer activator 3 Antibody
  • Polyomavirus enhancer activator 3 homolog Antibody
  • Protein PEA3 Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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