Anti-Ets-1 (phospho-T38) Antibody
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產(chǎn)品名稱: Anti-Ets-1 (phospho-T38) Antibody
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簡單介紹
Anti-Ets-1 (phospho-T38) Antibody
的詳細(xì)介紹
Overview
| Name: |
Anti-Ets-1 (phospho-T38) Antibody See all Ets1 primary antibodies
|
| Description: |
Rabbit polyclonal antibody to Ets-1 (phospho-T38) |
| Specificity: |
p-Ets-1 (T38) pAb detects endogenous levels of Ets-1 only when phosphorylated at Thr38. |
| Applications: |
WB, IHC, IF |
| Reactivity: |
Human, Mouse, Rat |
| Immunogen: |
Synthetic phosphopeptide derived from human ETS1 around the phosphorylation site of Threonine 38. |
| Host: |
Rabbit |
| Clonality: |
Polyclonal |
| Conjugate: |
Unconjugated |
| Molecular Weight: |
~ 54 kDa |
| Purity: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE). |
| Product Form: |
1mg/ml in PBS?with?0.1%?Sodium?Azide,?50%?Glycerol. |
Target
| Function: |
Transcription factor. Directly controls the expression of cytokine and chemokine genes in a wide variety of different cellular contexts. May control the differentiation, survival and proliferation of lymphoid cells. May also regulate angiogenesis through regulation of expression of genes controlling endothelial cell migration and invasion. |
| Tissue Specificity: |
Highly expressed within lymphoid cells. Isoforms c-ETS-1A and Ets-1 p27 are both detected in all fetal tissues tested, but vary with tissue type in ***** tissues. None is detected in brain or kidney. |
| Sequence Similarities: |
Belongs to the ETS family. |
| Post-Translational Modification: |
Sumoylated on Lys-15 and Lys-227, preferentially with SUMO2; which inhibits transcriptional activity. |
| Cellular Location: |
Cytoplasm. Nucleus.
Delocalizes from nucleus to cytoplasm when coexpressed with isoform Ets-1 p27. |
| Database Links: |
Entrez Gene: 2113?HumanEntrez Gene: 23871?MouseEntrez Gene: 24356?RatOmim: 164720?HumanSwissProt: P14921?HumanSwissProt: P27577?MouseSwissProt: P41156?RatUnigene: 369438?HumanUnigene: 292415?MouseUnigene: 88756?Rat |
| Synonyms: |
Avian erythroblastosis virus E26 (v ets) oncogene homolog 1 AntibodyC ets 1 protein Antibodyc-ets-1 AntibodyETS 1 AntibodyEts protein AntibodyETS proto-oncogene 1, transcription factor AntibodyETS1 AntibodyETS1 oncogene AntibodyETS1 protein AntibodyETS1_HUMAN AntibodyEWSR 2 AntibodyEWSR2 AntibodyFLJ10768 AntibodyOncogene ETS1 AntibodyP54 AntibodyProtein C-ets-1 Antibodyv ets avian erythroblastosis virus E2 oncogene homolog Antibodyv ets avian erythroblastosis virus E2 oncogene homolog 1 Antibodyv ets avian erythroblastosis virus E26 oncogene homolog 1 Antibodyv ets erythroblastosis virus E26 oncogene homolog 1 Antibodyv-ets erythroblastosis virus E26 oncogene homolog 1 Antibody |
| Information: |
Target information shown above is from the UniProt Consortium. |
